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Xofluza/baloxavir


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I heard a sales pitch from a drug rep on this med yesterday.  Essentially, it's a single dose anti-viral competing with Tamiflu/oseltamivir for the treatment of influenza patients.  The sales rep says it can shorten the duration of symptoms by 2+ days, similar to the claims that Tamiflu makes.

Does anyone have any experience with this?  I don't prescribe oseltamivir because it's costly, it has significant GI discomfort issues, and the actual data is mixed on its effectiveness.  Is this drug more effective in real use, or is it just more of the same?

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54 minutes ago, ohiovolffemtp said:

I heard a sales pitch from a drug rep on this med yesterday.  Essentially, it's a single dose anti-viral competing with Tamiflu/oseltamivir for the treatment of influenza patients.  The sales rep says it can shorten the duration of symptoms by 2+ days, similar to the claims that Tamiflu makes.

Does anyone have any experience with this?  I don't prescribe oseltamivir because it's costly, it has significant GI discomfort issues, and the actual data is mixed on its effectiveness.  Is this drug more effective in real use, or is it just more of the same?

https://pulmccm.org/infectious-disease-sepsis-review/fda-approves-new-anti-influenza-drug-xofluza-worked-better-than-oseltamivir/

Seems to offer quicker resolution of symptoms, reduction in viral load. Cost is elevated (of course). Most benefit was seen in OP populations, think there was some benefit in resolution of hypoxia for inpatients.

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