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I have always used the one gram dose of IM ceftriaxone since someone in my training days mentioned that 1000 mg of ceftriaxone covers incubating syphilis and any lower dose does not.

I like doxy > zithromax, but there is a compliance issue with bid dosing for a week vs single dose. Also zithromax covers a lot of other less common STIs, like mycoplasma genitalium(which is a common STI in Haiti) . Not sure if doxy does. Will check. 

https://www.pharmaceutical-journal.com/cpd-and-learning/learning-article/antibiotic-treatment-of-mycoplasma-genitalium-infection/20206592.article?firstPass=false

Looks like doxy works, but requires a 7 day course. 

These studies was done by friends of mine from my medical mission team:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228880/

https://pubmed.ncbi.nlm.nih.gov/25228665/

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REALLY dislike the idea of having to take a 7 days course versus 4 tabs at once of zithro..... just seems to encourage non-compliance...

as for 250mg versus 500mg versus 1gram.... blah, what ever the experts say......

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50 minutes ago, sas5814 said:

I live in Texas and the first thing I thought when I read the title of the post was "how many people live in Gonorrhea TX?"

It is near Chancre TX. "There's a yellow flow in Texas"

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