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PERC and WELLS negative massive PE


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file under better lucky than good.

Guy with zero PE risk factors or sx other than pleuritic chest pain. all stahndard questions negative.

any recent long distance travel? no

where you from? Kansas.

oh, how long have you been here? I just got here today.

how did you get here? I drove.

how long did it take? 10 hrs

that would be "long distance travel". no, I do it all the time. that is a short drive....

D-dimer 10x high nl

CTA chest massive PE involving main pulmonary artery....anticoagulated and admitted....

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Nice!  I remember hearing the authors of the PERC audio lecture at some point and they kept saying that their rule has never been wrong... people keep sending them case reports but when the authors dig in there they always find something to disqualify the patient... usually something stupid like the well's criteria of "PE likely number 1 diagnosis"... kind of a cheating trump card when you can always use that one in retrospect haha.

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I hate wells because of that subjective component. I usually use perc + common sense.

I would have thought pleurisy or chest wall strain more likely. I actually gave him toradol before he went to CT as I was basically just satisfying the d-dimer. I expected something like a tumor or other non-pe finding on ct that would explain the d-dimer.

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Had an old lady the other day - apparent CHF, only positive was her pacemaker implantation 10 days prior...abrupt SOB, crackly all around, CHF picture on CXR, some improvement with Lasix, but sats not coming up.  CT showed pile of PE's on the right.  Well's was 1.5.  We didn't D-Dimer due to age and recent surgical procedure.  What is it they tell us - treat the patient, not the machine or scores right?

 

SK

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2 hours ago, GetMeOuttaThisMess said:

There's a new requirement. Also treat the pt. satisfaction rating. Yes, I'm perturbed at present from a non-compliant patient earlier.


Sent from my iPad using Tapatalk

I had a pt yell at me because their in-room TV(not a fan) could not get a porn channel in the ER...

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7 hours ago, EMEDPA said:

I had a pt yell at me because their in-room TV(not a fan) could not get a porn channel in the ER...

They're obviously not that unwell at that point...and should be boot phuqued out the door if that's the case.  Luckily I don't worry too much about patient satisfaction scores...yet.

SK

 

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I always cover both the Wells Criteria and PERC rule but yeah, sometimes they don't mean jack. I had a 20 year old dude come in with calf pain after he slid down a ladder and scraped the calf along the way. His calf just looked swollen so I ultrasounded him and he had a DVT.  At that point I asked about  pulmonary symptoms like chest pain, shortness of breath, hemoptysis, racing heart. He said, "Not at all." When I walked out of the room he was like "Well, two weeks ago I had a weird chest pain that lasted a few seconds but that's it." Even though he was 20 I had a feeling I should scan him and he had bilateral PEs!

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Also, never forget syncoPE. I have had old people come in ONLY with complaints of syncope and I chest pain or shortness of breath, and totally normal vitals. I have scanned those people if they have VTE risk factors like recent surgery and have caught PEs.

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  • 3 weeks later...

Regardless if PERC and Wells are negative (I'd argue Wells isn't here in this circumstance which negates PERC as a R/O since the pre-test probability according to Wells is ~ 16% and PERC is only useful if pretest probability less than 15% and all criteria are negative) there is always a background noise of the population that develop PEs that will slip through these rules.  They are gauged to an approximate 1.6-2% miss rate regardless of what we think as clinicians - its why nothing will ultimately trump gestalt and why the specificity of the D-dimer is important.

Strong catch, E,

G

 

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4 hours ago, JMPAC said:

 


What kind of terrible ER doesn't have porn? I hope you at least provided him with some nudie magazines. It's the least you could do.

 

One of our nurses walked in on a guy that was cranking with his door open the other day...probably shouldn't encourage folks.

SK

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One of our nurses walked in on a guy that was cranking with his door open the other day...probably shouldn't encourage folks.
SK


Yikes! We had a homeless woman who kept sneaking into our waiting room to do that in the corner one night.

PS - hope you got the sarcasm in my porn comment!
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On 9/1/2017 at 6:03 PM, JMPAC said:

 


Yikes! We had a homeless woman who kept sneaking into our waiting room to do that in the corner one night.

PS - hope you got the sarcasm in my porn comment!

 

drop the C and you will be like me.

on a side note, if PE comes to mind, just test, clinical suspicion is your greatest indication for testing in the real world

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  • 2 months later...

Also, remember exactly what the D-dimer is testing... it too can be negative in the presence of a massive PE.  The D-dimer tests the breakdown of fibrin to fibrin-degradation product (FDP), and all you are testing is the rate at which that clot is actually being broken down.  Like all things in a biological system, it's a stochastic mechanism that operates based on the presence of enzyme(s) necessary to do their jobs, no more. 

G

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11 hours ago, kargiver said:

Also, remember exactly what the D-dimer is testing... it too can be negative in the presence of a massive PE.  The D-dimer tests the breakdown of fibrin to fibrin-degradation product (FDP), and all you are testing is the rate at which that clot is actually being broken down.  Like all things in a biological system, it's a stochastic mechanism that operates based on the presence of enzyme(s) necessary to do their jobs, no more. 

G

YUP, my understanding is that the d-dimer peaks after a week to 10 days and then declines to baseline, even if the clot persists. we had a young pt(40s) with massive b/l PEs and neg d-dimer who was sating 98% on RA, but had persistent tachycardia to 104 or so in our obs unit even while sleeping after passing a treadmill and 2 neg sets of enzymes. an observant doc scanned his chest and found the PEs.

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On 11/28/2017 at 0:37 PM, EMEDPA said:

YUP, my understanding is that the d-dimer peaks after a week to 10 days and then declines to baseline, even if the clot persists. we had a young pt(40s) with massive b/l PEs and neg d-dimer who was sating 98% on RA, but had persistent tachycardia to 104 or so in our obs unit even while sleeping after passing a treadmill and 2 neg sets of enzymes. an observant doc scanned his chest and found the PEs.

That's a scary scenario, but a good reminder why tachycardia can never be ignored.

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  • 3 months later...
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12 minutes ago, quietmedic said:

My major problem with PERC is the OCP thing.  99% of the young female population in on them, so...does every young female with OCPs and minimal c/p have a PE? Obviously not, but then the PERC score goes out the window.   Seems like a fundamental shortcoming of PERC.

+ PERC just gets them a dimer. if neg, you are probably done in the otherwise low risk pt.

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7 hours ago, EMEDPA said:

+ PERC just gets them a dimer. if neg, you are probably done in the otherwise low risk pt.

I know, but when it comes down to it, you aren't going to d-dimer every young female on OCPs with a little tachycardia....maybe it's your regular weekly pt having her usual weekly anxiety attack.  My point is that OCPs are so widespread that PERC is immediately useless in almost every female 12-52...and you certainly aren't going to d-dimer every single one of those patients, especially with a much more likely alternative diagnosis (which is a criteria in Wells, but surprisingly not in PERC).

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