A friend of mine had asked me about this. I had looked it up on Epocrates, but didnt know if it was dose-dependent.....
She was prescribed 25mg amitryptiline for migraines. It hasn't completely controlled her migraines though. Before she goes back to talk to her doctor, she asked if taking 25 mg topamax would both help with the migraines and counter weight gain. Epocrates interaction showed that you should use caution with this combo because of the additive effects, but I didnt know if its more for the 150mg amitryptiline or higher doses of topamax that you have to really worry about that. Any suggestions? I know that she's worried about increasing the amitryptiline more because shes already gained weight that shes still trying to lose back from when they originally tried an SSRI as a prophylactic.
I type fast and don't care about my grammer here. Don't bother criticizing it.
What would be the start/optimal dosing of valproic acid + topiramate? What about nortryptiline vs amitryptiline and side effect profile? Nort. is less correct?
just remember the nickname for topamax is dope-a-max gets you a little doppy - additive effects us make it worse